The Ludwig Boltzmann Institute for Translational Heart Failure Research (LBI.HF) is an independent research organization. It was founded  in 2011 within the framework of the Ludwig Boltzmann Gesellschaft based on a competitive international evaluation of the research program.

The LBI.HF shares the concept of all new Ludwig Boltzmann institutes to closely co-operate with designated institutional partners. Specifically, the LBI.HF was designed to provide a common platform for scientists from academia (i.e. Medical University of Graz, Karl-Franzens University Graz), industrial research and development (Bayer HealthCare), applied scientists (Austrian Institute of Technology) and health care providers (KAGes, GKK). In practice, this co-operation involves the exchange of ideas, methodology and expertise within a common research strategy. The purpose is to adopt a truly interdisciplinary, interactive, and translational approach that combines basic research and clinical expertise to effectively assess pathomechanisms and new diagnostic and therapeutic approaches in heart failure.